TRAM-34
TRAM-34 is a highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd = 20 nM) . Exhibits 200-1500-fold selectivity over KV, BKCa, KCa2, Na+, CRAC and Cl- channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli, and does not block cytochrome P450.
Product Specifications
CAS Number
289905-88-0
Product Name Alternative
TRAM-34 | TRAM34 | TRAM 34
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 3.5 mg/mL; 10.15 mM
Smiles
N1 (nccc1) C (c1ccccc1) (c1ccccc1) c1c (cccc1) Cl
Molecular Formula
C22H17ClN2
Molecular Weight
344.84
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-[ (2-Chlorophenyl) diphenylmethyl]-1H-pyrazole
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