SL-327
SL327 is a MEK inhibitor. SL327 blocks acquisition but not expression of lithium-induced conditioned place aversion: a behavioral and immunohistochemical study. SL327 had no affect on acquisition, expression, or extinction of EtOH-induced CPP in mice despite causing significant reduction of pERK levels in multiple brain regions. Additionally, although SL327 caused a generalized depression of locomotor activity, it did not prevent the development of EtOH-sensitization.
Product Specifications
CAS Number
305350-87-2
Product Name Alternative
SL327 | SL 327 | SL-327
Purity
>98% (HPLC)
Solubility
DMSO : 68 mg/mL 202.77 mM; Ethanol : 0.1 mg/mL 0.30 mM
Smiles
C1ccc (c (c1) C (=C (N) Sc1ccc (cc1) N) C#N) C (F) (F) F
Molecular Formula
C16H12F3N3S
Molecular Weight
335.35
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(E) -3-amino-3- ((4-aminophenyl) thio) -2- (2- (trifluoromethyl) phenyl) acrylonitrile
Available Sizes
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