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SL-327

SL327 is a MEK inhibitor. SL327 blocks acquisition but not expression of lithium-induced conditioned place aversion: a behavioral and immunohistochemical study. SL327 had no affect on acquisition, expression, or extinction of EtOH-induced CPP in mice despite causing significant reduction of pERK levels in multiple brain regions. Additionally, although SL327 caused a generalized depression of locomotor activity, it did not prevent the development of EtOH-sensitization.

Product Specifications

CAS Number

305350-87-2

Product Name Alternative

SL327 | SL 327 | SL-327

Purity

>98% (HPLC)

Solubility

DMSO : 68 mg/mL 202.77 mM; Ethanol : 0.1 mg/mL 0.30 mM

Smiles

C1ccc (c (c1) C (=C (N) Sc1ccc (cc1) N) C#N) C (F) (F) F

Molecular Formula

C16H12F3N3S

Molecular Weight

335.35

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(E) -3-amino-3- ((4-aminophenyl) thio) -2- (2- (trifluoromethyl) phenyl) acrylonitrile

Available Sizes

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