SC-202671
TCS JNK 5a, also called JNK Inhibitor IX , is a selective and potent inhibitor of JNK inhibitor. Exposure of human Jurkat T cells to SC-202671 targeting JNK2 and JNK3, caused apoptotic DNA fragmentation along with G2/M arrest, phosphorylation of Bcl-2, Mcl-1, and Bim, Δψm loss, and activation of Bak and caspase cascade.
Product Specifications
CAS Number
312917-14-9
Product Name Alternative
TCS JNK 5a, TCS-JNK-5a, JNK Inhibitor IX, SC-202671
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 51 mg/mL; 153.42 mM
Smiles
C1CCc2c (C1) c (c (s2) NC (=O) c1cccc2ccccc12) C#N
Molecular Formula
C20H16N2OS
Molecular Weight
332.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl) -1-naphthamide
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