BPTES
BPTES is a selective inhibitor of Glutaminase GLS1 (KGA), which is found in the kidney and brain, and is positively regulated by myc and strongly expressed in many tumors and tumor cell lines. BPTES has a K (i) of approx. 3 microM. BPTES inhibits the allosteric activation caused by phosphate binding and promotes the formation of an inactive complex.
Product Specifications
CAS Number
314045-39-1
Product Name Alternative
BPTES
Purity
>98% (HPLC)
Solubility
DMSO : 50 mg/mL 95.30 mM; H2O : < 0.1 mg/mL
Smiles
O=C (Cc1ccccc1) Nc1nnc (s1) CCSCCc1sc (nn1) NC (=O) Cc1ccccc1
Molecular Formula
C24H24N6O2S3
Molecular Weight
524.68
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N, N'- ((thiobis (ethane-2,1-diyl) ) bis (1,3,4-thiadiazole-5,2-diyl) ) bis (2-phenylacetamide)
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