5,7-Dihydroxychromone
5, 7-Dihydroxychromone isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 5, 7-Dihydroxychromone exerts neuroprotective effect against 6-OHDA-induced oxidative stress and apoptosis by activating Nrf2/ARE signal. 5, 7-Dihydroxychromone induces the translocation of Nrf2 to the nucleus and increases Nrf2/ARE binding activity which results in the up-regulation of the expression of Nrf2-dependent antioxidant genes, including HO-1, NQO1, and GCLc.
Product Specifications
CAS Number
31721-94-5
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (561.36 mM)
Smiles
C1=COC2=CC (=CC (=C2C1=O) O) O
Molecular Formula
C9H6O4
Molecular Weight
178.14
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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