Bilobalide
Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba. Bilobalide is important for producing several of the effects of Gingko biloba extracts. It has neuroprotective effects, as well as effects inducing the liver enzymes CYP3A1 and 1A2, which may be partially responsible for interactions between gingko and other herbal medicines or pharmaceutical drugs. Bilobalide has recently been found to be a negative allosteric modulator at the GABAA and GABAA-rho receptors. Of GABAA, it may possibly be selective for the subunits predominantly implicated in cognitive and memory functioning such as α1.
Product Specifications
CAS Number
33570-04-6
Product Name Alternative
(-) -Bilobalide | Bilobalide | Bilobalid
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL; 306.47 mM
Smiles
C1 (=O) O[C@H]2[C@@]3 ([C@]41[C@H] (C[C@@]3 (O) C (C) (C) C) OC (=O) C4) [C@H] (C (=O) O2) O
Molecular Formula
C15H18O8
Molecular Weight
326.3
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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