Echinatin
Echinatin disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits DNP-ATPase activity while stimulating range latent ATPase activity. Echinatin has significant antioxidant activities, it shows strong scavenging activity toward the ABTS + radical, it also dose-dependently inhibits LPS induced reactive oxygen species (ROS) production in RAW 264.7 cells and inhibits the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells.
Product Specifications
CAS Number
34221-41-5
Product Name Alternative
Echinatin | Retrochalcone
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 125 mg/mL (462.48 mM)
Smiles
COc2cc (O) ccc2/C=C/C (=O) c1ccc (O) cc1
Molecular Formula
C16H14O4
Molecular Weight
270.28
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(E) -3- (4-hydroxy-2-methoxyphenyl) -1- (4-hydroxyphenyl) prop-2-en-1-one
Available Sizes
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