Optovin
Optovin is a photoactive TRPA1 activator. Optovin activates human TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues. In animals with severed spinal cords, optovin treatment enables control of motor activity in the paralyzed extremities by localized illumination. These studies identify a light-based strategy for controlling endogenous TRPA1 receptors in vivo, with potential clinical and research applications in nontransgenic animals, including humans.
Product Specifications
CAS Number
348575-88-2
Product Name Alternative
Optovin
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 37 mg/mL; 117.31 mM
Smiles
S1C (=S) NC (=O) /C/1=C\c1c (n (c (c1) C) c1cnccc1) C
Molecular Formula
C15H13N3OS2
Molecular Weight
315.41
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(Z) -5- ((2,5-dimethyl-1- (pyridin-3-yl) -1H-pyrrol-3-yl) methylene) -2-thioxothiazolidin-4-one
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