Timosaponin AIII
Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM) . The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC50: 2.5 μM, BT474 cells; 6 μM, MDAMB231) . The Timosaponin AIII pro-apoptotic response is selective for tumor cells over normal cells but autophagy is induced in both.
Product Specifications
CAS Number
41059-79-4
Product Name Alternative
Timosaponin AIII
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 125 mg/mL (168.71 mM)
Smiles
[C@]12 ([C@@H]3[C@H] (C[C@H]1[C@H]1[C@H] (CC2) [C@@]2 ([C@H] (CC1) C[C@H] (CC2) O[C@H]1[C@H] (O[C@@H]2O[C@@H] ([C@H] ([C@@H] ([C@H]2O) O) O) CO) [C@H] ([C@H] ([C@H] (O1) CO) O) O) C) O[C@@]1 ([C@H]3C) CC[C@H] (CO1) C) C
Molecular Formula
C39H64O13
Molecular Weight
740.92
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
[ (25S) -5?-Spirostan-3?-yl]2-O- (?-D-glucopyranosyl) -?-D-galactopyranoside
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR10402839 96 Well
Monkey Creatine Kinase MM isoenzyme (CK MM) ELISA kit
Sign In for Pricing
View Details 
16906061 1.0 µg DNA
CSDA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 
115701A1-AAT 500 Tests
XFD750 Anti-non-human primates/ human CD157 Antibody *SY11B5*
Sign In for Pricing
View Details GA-E0049PC-01 48 Tests
Porcine cluster Of differentiation, CD44 ELISA Kit
Sign In for Pricing
View Details GA-E0049PC-02 96 Tests
Porcine cluster Of differentiation, CD44 ELISA Kit
Sign In for Pricing
View Details