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Y16

Y16, also known as RhoA-IN-Y16, is a RhoA inhibitor, Y16 blocks the binding of LARG, a DBL-family Rho guanine nucleotide exchange factor, with Rho (Kd = 80 nM) . Y16 specifically inhibits LARG catalyzed activation of RhoA and RhoA signaling pathways. Y16 blocks the growth and migration of MCF7 breast cancer cells.

Product Specifications

CAS Number

429653-73-6

Product Name Alternative

RhoA-IN-Y16 | Y16

Purity

>98% (HPLC)

Solubility

DMSO : 25 mg/mL 65.03 mM; H2O : < 0.1 mg/mL

Smiles

Cc1cc (ccc1) COc1cccc (c1) C=C1C (=O) NN (C1=O) c1ccccc1

Molecular Formula

C24H20N2O3

Molecular Weight

384.43

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(E) -4- (3- ((3-methylbenzyl) oxy) benzylidene) -1-phenylpyrazolidine-3,5-dione

Available Sizes

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