Y16
Y16, also known as RhoA-IN-Y16, is a RhoA inhibitor, Y16 blocks the binding of LARG, a DBL-family Rho guanine nucleotide exchange factor, with Rho (Kd = 80 nM) . Y16 specifically inhibits LARG catalyzed activation of RhoA and RhoA signaling pathways. Y16 blocks the growth and migration of MCF7 breast cancer cells.
Product Specifications
CAS Number
429653-73-6
Product Name Alternative
RhoA-IN-Y16 | Y16
Purity
>98% (HPLC)
Solubility
DMSO : 25 mg/mL 65.03 mM; H2O : < 0.1 mg/mL
Smiles
Cc1cc (ccc1) COc1cccc (c1) C=C1C (=O) NN (C1=O) c1ccccc1
Molecular Formula
C24H20N2O3
Molecular Weight
384.43
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(E) -4- (3- ((3-methylbenzyl) oxy) benzylidene) -1-phenylpyrazolidine-3,5-dione
Available Sizes
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