VU 0357121
VU0357121 is a positive allosteric modulator of mGlu5 receptors (EC50 = 33 nM) . Mutagenesis studies indicate that VU0357121 and related analogues bind to a yet uncharacterized allosteric site on mGlu (5), distinct from CPPHA, yet share a functional interaction with the MPEP site.
Product Specifications
CAS Number
433967-28-3
Product Name Alternative
VU-0357121, VU0357121, VU 0357121
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 50 mg/mL; 163.76 mM
Smiles
CCCCOc1ccc (cc1) C (=O) Nc1c (cc (cc1) F) F
Molecular Formula
C17H17F2NO2
Molecular Weight
305.32
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-Butoxy-N- (2,4-difluorophenyl) benzamide
Available Sizes
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