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VU 0357121

VU0357121 is a positive allosteric modulator of mGlu5 receptors (EC50 = 33 nM) . Mutagenesis studies indicate that VU0357121 and related analogues bind to a yet uncharacterized allosteric site on mGlu (5), distinct from CPPHA, yet share a functional interaction with the MPEP site.

Product Specifications

CAS Number

433967-28-3

Product Name Alternative

VU-0357121, VU0357121, VU 0357121

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 50 mg/mL; 163.76 mM

Smiles

CCCCOc1ccc (cc1) C (=O) Nc1c (cc (cc1) F) F

Molecular Formula

C17H17F2NO2

Molecular Weight

305.32

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4-Butoxy-N- (2,4-difluorophenyl) benzamide

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