Bimolane
Bimolane is a topoisomerase II inhibitor. Bimolane has been widely used in China as an anti-neoplastic agent and for the treatment of psoriasis. Bimolane is also a leukemogenic agent and is thought to exert its effects through the inhibition of topoisomerase II. The results of enzyme and DNA titration assays indicate that inhibition of topoisomerase II by bimolane occurred through interactions with DNA, similar to the mechanism seen with the epipodophyllotoxin-type inhibitors. These results provide evidence that bimolane is an inhibitor of topoisomerase II in vitro.
Product Specifications
CAS Number
74550-97-3
Product Name Alternative
AT-1727 | AT1727 | CCRIS 7574 | Bimolane
Purity
>98% (HPLC)
Smiles
N1 (C (=O) CN (CC1=O) CCN1CC (=O) N (C (=O) C1) CN1CCOCC1) CN1CCOCC1
Molecular Formula
C20H32N6O6
Molecular Weight
452.51
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1- (morpholin-4-ylmethyl) -4-[2-[4- (morpholin-4-ylmethyl) -3,5-dioxopiperazin-1-yl]ethyl]piperazine-2,6-dione
Available Sizes
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