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VER-50589

VER-50589 is a potent Hsp90 inhibitor. VER-50589 inhibits Hsp90 with an IC50 value of 21 nM. It produces a mean cellular antiproliferative GI50 value of 78 nM when tested against a human cancer cell line panel. VER-50589 shows favorable pharmacokinetics and impairs tumor growth in animals.

Product Specifications

CAS Number

747413-08-7

Product Name Alternative

VER50589 | VER 50589 | VER-50589

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 48 mg/mL; 123.46 mM

Smiles

C1 (cc (c (cc1O) O) c1c (c2ccc (cc2) OC) c (no1) C (=O) NCC) Cl

Molecular Formula

C19H17ClN2O5

Molecular Weight

388.8

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

5- (5-chloro-2,4-dihydroxyphenyl) -N-ethyl-4- (4-methoxyphenyl) isoxazole-3-carboxamide

Available Sizes

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