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Sanggenone C

Sanggenone C inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. Sanggenone C and O inhibited NO production and iNOS expression by suppressing NF-κB activity and IκBα activation; inhibited TNF-alpha -stimulated PMN-HSC adhesion and expression of VCAM-1 by suppressing the activation of NF-kappaB.

Product Specifications

CAS Number

80651-76-9

Product Name Alternative

Sanggenone C | Sanggenon C

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 100 mg/mL (141.10 mM)

Smiles

CC1=CC (C (C (C1) C2=C (C=C (C=C2) O) O) C (=O) C3=C (C=C (C=C3) O) O) C4=C (C=C5C (=C4O) C (=O) C6 (C (O5) (C7=C (O6) C=C (C=C7) O) CC=C (C) C) O) O

Molecular Formula

C40H36O12

Molecular Weight

708.71

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2- ((1S,2R,3S) -2- (2,4-dihydroxybenzoyl) -2',4'-dihydroxy-5-methyl-1,2,3,6-tetrahydro-[1,1'-biphenyl]-3-yl) -1,3,8,10a-tetrahydroxy-5a- (3-methylbut-2-en-1-yl) -5a,10a-dihydro-11H-benzofuro[3,2-b]chromen-11-one

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