Sanggenone C
Sanggenone C inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. Sanggenone C and O inhibited NO production and iNOS expression by suppressing NF-κB activity and IκBα activation; inhibited TNF-alpha -stimulated PMN-HSC adhesion and expression of VCAM-1 by suppressing the activation of NF-kappaB.
Product Specifications
CAS Number
80651-76-9
Product Name Alternative
Sanggenone C | Sanggenon C
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (141.10 mM)
Smiles
CC1=CC (C (C (C1) C2=C (C=C (C=C2) O) O) C (=O) C3=C (C=C (C=C3) O) O) C4=C (C=C5C (=C4O) C (=O) C6 (C (O5) (C7=C (O6) C=C (C=C7) O) CC=C (C) C) O) O
Molecular Formula
C40H36O12
Molecular Weight
708.71
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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