Fostemsavir
Fostemsavir, also known as BMS-663068, is a oral, safe and effective HIV-1 attachment inhibitor. BMS-663068 is a prodrug of the small-molecule inhibitor BMS-626529, which inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and interfering with the attachment of virus to CD4+ T-cells. (In Vivo) :Fostemsavir (BMS-663068) has good antiviral activity in subjects infected with virus shown to be susceptible (IC50, <100 nM) to the agent.
Product Specifications
CAS Number
864953-29-7
Product Name Alternative
BMS-663068 | BMS 663068 | Fostemsavir
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL 171.38 mM H2O : 20 mg/mL 34.28 mM
Smiles
COc1cnc (-n2cnc (C) n2) c2n (COP (O) (O) =O) cc (C (=O) C (=O) N3CCN (CC3) C (=O) c3ccccc3) c12
Molecular Formula
C25H26N7O8P
Molecular Weight
583.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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