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Fostemsavir

Fostemsavir, also known as BMS-663068, is a oral, safe and effective HIV-1 attachment inhibitor. BMS-663068 is a prodrug of the small-molecule inhibitor BMS-626529, which inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and interfering with the attachment of virus to CD4+ T-cells. (In Vivo) :Fostemsavir (BMS-663068) has good antiviral activity in subjects infected with virus shown to be susceptible (IC50, <100 nM) to the agent.

Product Specifications

CAS Number

864953-29-7

Product Name Alternative

BMS-663068 | BMS 663068 | Fostemsavir

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 100 mg/mL 171.38 mM H2O : 20 mg/mL 34.28 mM

Smiles

COc1cnc (-n2cnc (C) n2) c2n (COP (O) (O) =O) cc (C (=O) C (=O) N3CCN (CC3) C (=O) c3ccccc3) c12

Molecular Formula

C25H26N7O8P

Molecular Weight

583.5

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(3- (2- (4-benzoylpiperazin-1-yl) -2-oxoacetyl) -4-methoxy-7- (3-methyl-1H-1,2,4-triazol-1-yl) -1H-pyrrolo[2,3-c]pyridin-1-yl) methyl dihydrogen phosphate

Available Sizes

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