Dovitinib lactate hydrate
Dovitinib (TKI258) Lactate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
Product Specifications
CAS Number
915769-50-5
Purity
>98% (HPLC)
Smiles
CC (C (=O) O) O.CN1CCN (CC1) C2=CC3=C (C=C2) N/C (=C\4/C (=C5C (=NC4=O) C=CC=C5F) N) /N3.O
Molecular Formula
C24H27FN6O4
Molecular Weight
482.51
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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