Ranolazine
Ranolazine is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium channels during myocardial ischemia in rabbits by altering the intracellular sodium level. (In Vivo) :Ranolazine (Bolus injection 10 mg/kg and infusion 9.6 mg/kg/h; bolus injection; for 145 minutes; male Wistar rats) treatment significantly reduces infarct size and cardiac troponin T release in rats subjected to left anterior descending coronary artery occlusion-reperfusion.
Product Specifications
CAS Number
95635-55-5
Product Name Alternative
CVT 303 | RS 43285-003
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : 125 mg/mL 292.37 mM
Smiles
COc1ccccc1OCC (O) CN1CCN (CC (=O) Nc2c (C) cccc2C) CC1
Molecular Formula
C24H33N3O4
Molecular Weight
427.54
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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