S-Isocorydine (+)
Isocorydine is an alkaloid from root tubers of Stephania Kwangsiensis H.S. Lo. (In Vitro) :Isocorydine (0-400 ug/ml; 48 hours) show a significant decrease in the IC50 for ICD and DOX, the CI values are 0.605, 0.644, 0.804, and 0.707 respectively for Huh-7, Hep-G2, SNU-449 and SNU-387.Isocorydine (0-400 ug/ml; 48 hours) abrogates DOX-induced upregulation of mesenchymal markers and the downregulation of epithelial markers in human HCC cell lines. (In Vivo) :Isocorydine (intraperitoneal injection; 0.4 mg/kg; every 2 days for 2 weeks) retards the tumor growth, but the combined treatment of Doxorubicin (DOX) or ICD significantly inhibits tumor growth.
Product Specifications
CAS Number
475-67-2
Product Name Alternative
Isocorydine | Luteanin | d-Isocorydine | NSC32979
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 20 mg/mL (58.58 mM)
Smiles
CN1CCc2cc (c (c3c2[C@@H]1Cc1c3c (c (cc1) OC) O) OC) OC
Molecular Formula
C20H23NO4
Molecular Weight
341.41
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(S) -1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de, g]quinolin-11-ol
Available Sizes
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