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Dehydrocostus Lactone

Dehydrocostus Lactone is a natural sesquiterpene first isolated from costus root, which is used in traditional medicine. Dehydrocostus lactone, a natural sesquiterpene lactone, suppresses the biological characteristics of glioma, through inhibition of the NF-κB/COX-2 signaling pathway by targeting IKKβ. Dehydrocostus Lactone Suppresses Proliferation of Human Chronic Myeloid Leukemia Cells Through Bcr/Abl-JAK/STAT Signaling Pathways. Dehydrocostus Lactone Inhibits Proliferation, Antiapoptosis, and Invasion of Cervical Cancer Cells Through PI3K/Akt Signaling Pathway.

Product Specifications

CAS Number

477-43-0

Product Name Alternative

Dehydrocostus Lactone | (-) -Dehydrocostus lactone.

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 62.5 mg/mL; 271.39 mM

Smiles

C=C1CC[C@@H]2[C@@H] ([C@@H]3[C@H]1CCC3=C) OC (=O) C2=C

Molecular Formula

C15H18O2

Molecular Weight

230.3

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(3aS,6aR,9aR,9bS) -3,6,9-trimethylenedecahydroazuleno[4,5-b]furan-2 (3H) -one

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