Pinocembrin

Pinocembrin is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis. (In Vitro) :Pinocembrin (5, 10, 25, 50, 100 or 200 μM, 24 hours) significantly reduces cell viability of RBL-2H3 cells.Pinocembrin (25 or 50 μM) suppresses iNOS, PGE-2 and COX-2 levels, increases p38-Mapk and IкB-α, and inhibits phosphorylation of IкB-α.