Senecionine N-oxide

Senecionine n-oxide is the primary product of pyrrolizidine alkaloid biosynthesis in root cultures of Senecio vulgaris. Senecionine N-oxide has anti-cancer activity[1][2].

Product Specifications

CAS Number

[13268-67-2]

UNSPSC

12352005

Hazard Statement

H300+H310+H330

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/senecionine-n-oxide.html

Purity

99.11

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(O[C@]1([H])CC[N+]2([O-])[C@]1([H])C(COC([C@](C)(O)[C@H](C)C/3)=O)=CC2)C3=C/C

Molecular Formula

C18H25NO6

Molecular Weight

351.39

Precautions

H300+H310+H330

References & Citations

[1]Thomas Hartmann, et al. Senecionine n-oxide, the primary product of pyrrolizidine alkaloid biosynthesis in root cultures of Senecio vulgaris. Phytochemistry, Volume 26, Issue 6, 1987, Pages 1639-1643|[2]Kupchan SM, et al. Tumor inhibitors. XXII. Senecionine and senecionine N-oxide, the active principles of Senecio triangularis. J Pharm Sci. 1967 Apr;56 (4) :541-3.