Isofraxidin
Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.
Product Specifications
CAS Number
486-21-5
Product Name Alternative
Isofraxidin | Phytodolor
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (1125.16 mM)
Smiles
COC1=C (C (=C2C (=C1) C=CC (=O) O2) OC) O
Molecular Formula
C11H10O5
Molecular Weight
222.19
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
7-Hydroxy-6,8-dimethoxychromen-2-one
Available Sizes
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