Nordihydroguaiareticacid
INSM-18, also known as nordihydroguaiaretic acid, NDGA and masoprocol, is a naturally occurring antioxidant dicatechol originally derived from the creosote bush Larrea divaricatta with antipromoter, anti-inflammatory, and antineoplastic activities. NDGA directly inhibits activation of two receptor tyrosine kinases (RTKs), the insulin-like growth factor receptor (IGF-1R) and the c-erbB2/HER2/neu receptor, resulting in decreased proliferation of susceptible tumor cell populations.
Product Specifications
CAS Number
500-38-9
Product Name Alternative
INSM18 | INSM-18, INSM 18, masoprocol
Purity
>98% (HPLC)
Solubility
DMSO : 75 mg/mL 248.05 mM
Smiles
CC (CC1=CC (=C (C=C1) O) O) C (C) CC2=CC (=C (C=C2) O) O
Molecular Formula
C18H22O4
Molecular Weight
302.37
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4,4'- ((2R,3S) -2,3-dimethylbutane-1,4-diyl) bis (benzene-1,2-diol)
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