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PNU-120596

PNU-120596, also known as NSC 216666, is α7 nicotinic acetylcholine receptor positive allosteric modulator. PNU-120596 reverses a sub-chronic phencyclidine-induced cognitive deficit in the attentional set-shifting task in female rats. PNU-120596 augments the effects of donepezil on learning and memory in aged rodents and non-human primates.

Product Specifications

CAS Number

501925-31-1

Product Name Alternative

PNU-120596 | PNU 120596 | PNU120596 | NSC 216666

Purity

>98% (HPLC)

Solubility

DMSO : 50 mg/mL 160.40 mM

Smiles

COc1cc (OC) c (NC (=O) Nc2noc (C) c2) cc1Cl

Molecular Formula

C13H14ClN3O4

Molecular Weight

311.72

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1- (5-Chloro-2,4-dimethoxyphenyl) -3- (5-methylisoxazol-3-yl) urea

Available Sizes

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