Herniarin
Herniarin is a natural coumarin with antitumor effect. (In Vitro) :Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5 μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
Product Specifications
CAS Number
531-59-9
Product Name Alternative
7-Methoxycoumarin | Methyl umbelliferyl ether
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 125 mg/mL; 709.54 mM
Smiles
COc1ccc2ccc (=O) oc2c1
Molecular Formula
C10H8O3
Molecular Weight
176.17
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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