Sesamol
Sesamol could decrease lung inflammation and lipopolysaccharide (LPS) -induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 signaling and blocking the NF-κB and MAPK signaling pathways and inhibits melanin biosynthesis by down-regulating tyrosinase activity and melanin production via regulation of gene expression of melanogenesis-related proteins through modulation of MITF activity, which promotes phosphorylation of p38 and JNK in melan-a cells.
Product Specifications
CAS Number
533-31-3
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : ≥ 100 mg/mL (724.01 mM)
Smiles
C1Oc2c (O1) cc (cc2) O
Molecular Formula
C7H6O3
Molecular Weight
138.12
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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