Rat Monoclonal [clone M1/70.15] (IgG2b) to Mouse ITGAM / CD11b
Product Specifications
Gene Name
[ITGAM]
NCBI Gene ID
3684
Reactivity
Human, Mouse, Rabbit
Storage Conditions
Long term: -20 °C; Short term: +4 °C. Avoid repeat freeze-thaw cycles.
Specificity
Recognizes the murine CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone M1/70.15 has been reported to block iC3b binding to its receptor. This product is routinely tested in flow cytometry on mouse peritoneal macrophages.
Other Gene Names
[ITGAM; ITGAM; CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; CD11B; CR3A]
Short Name
[ITGAM / CD11b]
Other Product Names
[integrin alpha-M isoform 2; Integrin alpha-M; integrin alpha-M; CR-3 alpha chain; antigen CD11b (p170); leukocyte adhesion receptor MO1; CD11 antigen-like family member B; macrophage antigen alpha polypeptide; cell surface glycoprotein MAC-1 subunit alpha; neutrophil adherence receptor alpha-M subunit; integrin, alpha M (complement component 3 receptor 3 subunit); CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD_antigen: CD11b]
NCBI GI Number
88501734
NCBI Accession Number
NP_000623.2
NCBI GB Accession Number
NM_000632.3
Uniprot Accession Number
P11215
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
