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Loureirin A

Loureirin A has an inhibitory effect on platelet activation perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen collagen-related peptide (CRP) ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs) -seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4inhibiting the synthesis and secretion of α- SMATGF- β1and the proliferation of HSCs.

Product Specifications

CAS Number

119425-89-7

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 86.6 mg/mL (302.46 mM)

Smiles

COc1ccc (CCC (=O) c2ccc (O) cc2) c (OC) c1

Molecular Formula

C17H18O4

Molecular Weight

286.32

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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