Loureirin A
Loureirin A has an inhibitory effect on platelet activation perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen collagen-related peptide (CRP) ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs) -seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4inhibiting the synthesis and secretion of α- SMATGF- β1and the proliferation of HSCs.
Product Specifications
CAS Number
119425-89-7
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 86.6 mg/mL (302.46 mM)
Smiles
COc1ccc (CCC (=O) c2ccc (O) cc2) c (OC) c1
Molecular Formula
C17H18O4
Molecular Weight
286.32
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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