Tetrahydroxyl diphenylethylene-2-o-gluco
EH-201 is a low MW inducer of erythropoietin. EH-201 induces expression of erythropoietin PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo EH-201 treatment restores memory impairment as assessed by the passive avoidance test in SD Aβ and KA mouse models. In the hippocampus of mice given EH-201 in their diet levels of erythropoietin PGC-1α and haemoglobin were increased. Treatment with EH-201 might be a therapeutic strategy for memory impairment in neurodegenerative disease physiological ageing or traumatic brain injury.
Product Specifications
CAS Number
55327-45-2
Product Name Alternative
EH-201
Purity
>98% (HPLC)
Solubility
DMSO:10 mM
Smiles
OC[C@H]1O[C@@H] (Oc2c (O) cc (O) cc2\C=C\c2ccc (O) cc2) [C@H] (O) [C@@H] (O) [C@@H]1O
Molecular Formula
C20H22O9
Molecular Weight
406.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(2S3R4S5S6R) -2- (24-dihydroxy-6- ((E) -4-hydroxystyryl) phenoxy) -6- (hydroxymethyl) tetrahydro-2H-pyran-345-triol
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