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Cucurbitacin IIA

Cucurbitacin IIA can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.

Product Specifications

CAS Number

58546-34-2

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 25 mg/mL (44.43 mM)

Smiles

CC (=O) OC (C) (C) CCC (=O) C (C) (C1C (CC2 (C1 (CC (=O) C3 (C2CC=C4C3CC (C (C4 (C) C) O) O) C) C) C) O) O

Molecular Formula

C32H50O8

Molecular Weight

562.74

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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