Licochalcone B
Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. LCB and Licochalcone D (LCD) significantly reduced the LPS-induced production of NO, TNFalpha and MCP-1. A novel LCB derivative compound: (E) -3- (3, 4-dihydroxy-2-methoxyphenyl) -1- (2, 4-dihydroxyphenyl) prop-2-en-1-one inhibits inflammatory reactions in macrophages and protects mice from endotoxin shock.
Product Specifications
CAS Number
58749-23-8
Product Name Alternative
Licochalcone B | Licochalcone-B
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 83.33 mg/mL (291.08 mM)
Smiles
COC1=C (C=CC (=C1O) O) C=CC (=O) C2=CC=C (C=C2) O
Molecular Formula
C16H14O5
Molecular Weight
286.28
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(E) -1- (3,4-dihydroxy-2-methoxyphenyl) -3- (4-hydroxyphenyl) prop-2-en-1-one
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