Thiocolchicoside
Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals. (In Vitro) :Thiocolchicoside (0.001, 0.1, 1, 10, 100 μM) reduces the amplitude of eIPSCs in a concentration-dependent manner with this effect being significant at 0.1 μM and maximal at 10 μM.
Product Specifications
CAS Number
602-41-5
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (443.56 mM)
Smiles
CC (=O) NC1CCC2=CC (=C (C (=C2C3=CC=C (C (=O) C=C13) SC) OC) OC) OC4C (C (C (C (O4) CO) O) O) O
Molecular Formula
C27H33NO10S
Molecular Weight
563.61
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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