BIIL-260 (hydrochloride)
BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B (4) receptor LTB4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with Ki values of 1.7 nM[1].
Product Specifications
CAS Number
[192581-24-1]
Product Name Alternative
Xanthothricin; Toxoflavine; PKF-118-310
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/biil-260-hydrochloride.html
Purity
99.90
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
N=C(C1=CC=C(OCC2=CC=CC(COC3=CC=C(C(C)(C4=CC=C(O)C=C4)C)C=C3)=C2)C=C1)N.[H]Cl
Molecular Formula
C30H31ClN2O3
Molecular Weight
503.03
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LTB4
Available Sizes
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