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Cefoperazone

Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. It can inhibit rMrp2-mediated [3H]E217βG uptake (IC50: 199 μM) .

Product Specifications

CAS Number

62893-19-0

Product Name Alternative

Cefobid | Cefozon | T1551 | T 1551

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 100 mg/mL 154.88 mM H2O : < 0.1 mg/mL

Smiles

[H][C@]12SCC (CSC3=NN=NN3C) =C (N1C (=O) [C@H]2NC (=O) [C@H] (NC (=O) N1CCN (CC) C (=O) C1=O) C1=CC=C (O) C=C1) C (O) =O

Molecular Formula

C25H27N9O8S2

Molecular Weight

645.67

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(6R,7R) -7- ((R) -2- (4-ethyl-2,3-dioxopiperazine-1-carboxamido) -2- (4-hydroxyphenyl) acetamido) -3- (((1-methyl-1H-tetrazol-5-yl) thio) methyl) -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

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