Cefoperazone
Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. It can inhibit rMrp2-mediated [3H]E217βG uptake (IC50: 199 μM) .
Product Specifications
CAS Number
62893-19-0
Product Name Alternative
Cefobid | Cefozon | T1551 | T 1551
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL 154.88 mM H2O : < 0.1 mg/mL
Smiles
[H][C@]12SCC (CSC3=NN=NN3C) =C (N1C (=O) [C@H]2NC (=O) [C@H] (NC (=O) N1CCN (CC) C (=O) C1=O) C1=CC=C (O) C=C1) C (O) =O
Molecular Formula
C25H27N9O8S2
Molecular Weight
645.67
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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