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Mitoxantrone

Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.

Product Specifications

CAS Number

65271-80-9

Product Name Alternative

Mitozantrone

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 150 mg/mL; 337.47 mM

Smiles

OCCNCCNc1ccc (NCCNCCO) c2c1C (=O) c1c (O) ccc (O) c1C2=O

Molecular Formula

C22H28N4O6

Molecular Weight

444.48

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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