Mitoxantrone
Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.
Product Specifications
CAS Number
65271-80-9
Product Name Alternative
Mitozantrone
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 150 mg/mL; 337.47 mM
Smiles
OCCNCCNc1ccc (NCCNCCO) c2c1C (=O) c1c (O) ccc (O) c1C2=O
Molecular Formula
C22H28N4O6
Molecular Weight
444.48
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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