AKBA

AKBA is an antiangiogenic and neuroprotective agent, reducing the impact of proliferative retinopathies, protecting neurons against ischemic injury involving the Nrf2/HO-1 pathway. It selectively inhibits 5-lipoxygenase (IC50 = 1.5 μM) in an enzyme-directed, nonredox, and noncompetitive manner.2 3-acetyl-11-keto-β-Boswellic acid and other members of the boswellic acid family have been studied for potential use in the control of inflammatory diseases, including arthritis and cancer.

Product Specifications

CAS Number

67416-61-9

Product Name Alternative

AKBA | 3-O-acetyl-11-keto-β-Boswellic acid

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 5.2 mg/mL; 10.14 mM

Smiles

CC1CCC2 (CCC3 (C (=CC (=O) C4C3 (CCC5C4 (CCC (C5 (C) C (=O) O) OC (=O) C) C) C) C2C1C) C) C

Molecular Formula

C32H48O5

Molecular Weight

512.73

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS) -3-acetyloxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid