MRS 2578
MRS-2578 is a selective antagonist of P2Y6 nucleotide receptors (IC50 values are 37 and 98 nM at human and rat P2Y6 receptors respectively) . Activation of P2Y6 receptor amplifies mucosal adenosine triphosphate release underlying bladder overactivity in patients with benign prostatic hyperplasia. Therefore, selective P2Y6 receptor blockade as a novel therapeutic strategy is potentially useful to control persistent storage symptoms in obstructed patients.
Product Specifications
CAS Number
711019-86-2
Product Name Alternative
MRS-2578 | MRS2578 | MRS 2578
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 80 mg/mL; 169.25 mM
Smiles
S=C=NC1=CC=CC (NC (=S) NCCCCNC (=S) NC2=CC (=CC=C2) N=C=S) =C1
Molecular Formula
C20H20N6S4
Molecular Weight
472.67
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1,1'- (butane-1,4-diyl) bis (3- (3-isothiocyanatophenyl) thiourea)
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