Praeruptorin C
Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors and regulating the Bcl-2 family. Praeruptorin C can reduce vascular hypertrophy in isolated rat hypertrophied smooth muscle cells, and this is associated with improvement of smooth muscle cells [Ca2+]i level, nitric oxide content and cellular signal transdution of protein kinase C and Gi.
Product Specifications
CAS Number
72463-77-5
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 25 mg/mL (58.35 mM)
Smiles
CC=C (C) C (=O) OC1C (C2=C (C=CC3=C2OC (=O) C=C3) OC1 (C) C) OC (=O) CC (C) C
Molecular Formula
C24H28O7
Molecular Weight
428.48
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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