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Praeruptorin C

Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors and regulating the Bcl-2 family. Praeruptorin C can reduce vascular hypertrophy in isolated rat hypertrophied smooth muscle cells, and this is associated with improvement of smooth muscle cells [Ca2+]i level, nitric oxide content and cellular signal transdution of protein kinase C and Gi.

Product Specifications

CAS Number

72463-77-5

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 25 mg/mL (58.35 mM)

Smiles

CC=C (C) C (=O) OC1C (C2=C (C=CC3=C2OC (=O) C=C3) OC1 (C) C) OC (=O) CC (C) C

Molecular Formula

C24H28O7

Molecular Weight

428.48

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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