Praeruptorin A
Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca (2+) /calmodulin-CaMKIV-CREB-NFATc1 and/or Ca (2+) /calmodulin-calcineurin-NFATc1 signaling axis.
Product Specifications
CAS Number
73069-27-9
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 33.33 mg/mL (86.26 mM)
Smiles
C/C=C (/C) \C (=O) O[C@H]1[C@H] (c2c (ccc3c2oc (=O) cc3) OC1 (C) C) OC (=O) C
Molecular Formula
C21H22O7
Molecular Weight
386.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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