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Praeruptorin A

Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca (2+) /calmodulin-CaMKIV-CREB-NFATc1 and/or Ca (2+) /calmodulin-calcineurin-NFATc1 signaling axis.

Product Specifications

CAS Number

73069-27-9

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 33.33 mg/mL (86.26 mM)

Smiles

C/C=C (/C) \C (=O) O[C@H]1[C@H] (c2c (ccc3c2oc (=O) cc3) OC1 (C) C) OC (=O) C

Molecular Formula

C21H22O7

Molecular Weight

386.4

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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