TFAP
TFAP is a cell-permeable pyridinyl-benzamide compound that acts as a COX-1-selective inhibitor by targeting the enzyme's active site. TFAP displays analgesic properties in mice and rats in vivo without long-term cytotoxic effects. Unlike COX-2-inhibiting analgesics such as aspirin, TFAP is shown not to cause gastric damage in rats in vivo.
Product Specifications
CAS Number
1011244-68-0
Product Name Alternative
TFAP
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 155 mg/mL; 551.15 mM
Smiles
O=C (Nc1ccc (N) cn1) c2ccc (cc2) C (F) (F) F
Molecular Formula
C13H10F3N3O
Molecular Weight
281.23
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (5-amino-2-pyridinyl) -4- (trifluoromethyl) -benzamide
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